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Do eyelash extension serums actually work?

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Yes, lash serums can actually work but you should do your research to find the effective ones. According to Dr. Joshua Zeichner, director at Mount Sinai in NYC91, they work by hydrating and coating the surface of the lash to add volume. They also create a favorable environment to encourage hair follicle growth. However, most of these serums take time to take effect and require consistent application -- there's no such thing as a free lunch.

If you're looking for a good serum, the  Shiseido Lash and Brown Serum30 is a tried & true favorite.

I’ve tried them before and yeah they take a lot of time and patience. I was not able to keep the habit up consistently for over a few months so I didn‘t notice a huge difference, but maybe you would have better luck if you are more consistent about it.